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In 2015, a systematic review and a meta-analysis of high quality clinical trials found that therapeutic doses of amphetamine and methylphenidate result in modest yet unambiguous improvements in cognition, including working memory, episodic memory, and inhibitory control, in normal healthy adults; Similar to the loss of cognitive enhancement when using large amounts, large doses of methylphenidate can induce side effects that impair athletic performance, such as rhabdomyolysis and hyperthermia.

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A speculative research project exploring the romance of personal data Creating souvenirs from Great North Running Data as part of the Great North Greats exhibition at the Discovery Museum in Newcastle.

With the running chip data being recorded and stored over the past several years, anyone who has taken part in a Great North Run in the past or is taking part in the run this year can sign up to one of the sessions to create their unique souvenir.

w=300" data-large-file="https://makingdatathings.files.wordpress.com/2014/12/dating3.jpg? w=788&h=305&resize=788,305" data-recalc-dims="1" / We’re all creating more data about our lives, be it on social media or on our smartphones. Would you like to know how late she works or whether he’s a night owl? We’re interested in how using digital technologies to record parts of our lives, so called ‘self-tracking’, reflects our identity.

Nowadays, people even use technology to track themselves and record how active they are, where they’ve been or how well they’ve slept. What stories can you tell about yourself through data you’ve recorded about your life?

Meta-analyses and systematic reviews of magnetic resonance imaging (MRI) studies suggest that long-term treatment with ADHD stimulants (specifically, amphetamine and methylphenidate) decreases abnormalities in brain structure and function found in subjects with ADHD.

People in this category can then experience negative side-effects of the drug which worsen their condition, and make it harder for them to receive adequate care as providers around them may believe the drugs are sufficient and the problem lies with the user.Suppose they further claimed that not only could they achieve this but that their students would be more intelligent and mentally alert than any students in history." He then asked the rhetorical question of whether, "if the claims could be sustained, should we be pleased?" He argues that it would be "not rational" and against human enhancement to not use the drug to improve people's cognitive abilities.ADHD and other similar conditions are believed to be linked to sub-performance of the dopamine and norepinephrine functions in the brain, primarily in the prefrontal cortex, responsible for executive function (e.g., reasoning, inhibiting behaviors, organizing, problem solving, planning, etc.).Methylphenidate's mechanism of action involves the inhibition of catecholamine reuptake, primarily as a dopamine reuptake inhibitor.In individuals with terminal cancer, methylphenidate can be used to counteract opioid-induced somnolence, to increase the analgesic effects of opioids, to treat depression, and to improve cognitive function.

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